Civale spent his first few seasons in the minor leagues, playing for teams such as the Mahoning Valley Scrappers, the Lake County Captains, the Lynchburg Hillcats, and the Akron RubberDucks. In 2019, he was called up to the major leagues for the first time, and he has been a fixture in the Cleveland rotation ever since.

Civale's best plays have come in the form of his pitching performances. In his debut game in 2019, he pitched six innings with six strikeouts against the Detroit Tigers, earning the win. Civale's success continued throughout the 2019 season, and in 2020 he led the American League in hits allowed and highest batting average against.

Despite being sidelined for much of the 2021 season due to a finger injury, Civale bounced back in September to finish the season with a 12–5 record and a 3.84 ERA in 21 starts. Civale's best play of the 2021 season came on October 3, when he pitched six scoreless innings against the Texas Rangers, earning the win in Cleveland's final game under their Indians nickname.

Civale's success on the field has led to recognition off the field, too. In January 2023, he agreed to a one-year, $2.6 million contract with the Cleveland Guardians, avoiding salary arbitration.

In conclusion, Aaron Civale has had an impressive career so far in MLB, and his best plays have come in the form of his pitching performances. Civale's success in college and the minor leagues has translated well to the major leagues, and he has quickly become a key player for the Cleveland Guardians. With his talent and drive, there's no doubt that Civale will continue to make his mark on the sport in the years to come.